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  • admin test

    发表于 2008-08-24

    测试一把 ...全文

  • 汤汤 (浙江) 细胞处理缺陷蛋白质量控制机制

    发表于 2008-07-31

    日本科学家在新一期美国《科学》(Science)杂志网络版上介绍说,他们进一步探明了细胞处理缺陷蛋白质的质量控制机制。这一成果可能有助于寻找治疗阿尔茨海默氏症等疾病的新方法。   日本京都大学教授永田和宏等人发现,细胞内质网上有3种蛋白质巧妙分工合作,检测、分解并处理有缺陷的蛋白质,承担着对细胞内的蛋白质进行质量管理... ...全文

  • 汤汤 (浙江) 揭秘显微镜下的美丽细胞(组图)---from bioon

    发表于 2008-05-12 评论: 1 好评: 5

    显微技术的发展,让科学家可以更容易深入微观世界。但在普通显微镜下,细胞的模样千篇一律,很难区分。为此,科学家发明了多种方法:利用基因工程技术改造细胞,用染料给细胞染色……最终,呈现在显微镜视野里的,不再是单调的细胞,而是五彩斑斓的美丽景象。  不论我们喜不喜欢眼前的物体,眼睛永远用同一种方式采集信息:视网膜上的细胞捕捉光... ...全文

  • 汤汤 (浙江) 华人学者发现“自我吞噬”关键蛋白

    发表于 2008-05-06

    一个叫做“自我吞噬”的自我消化过程促进了红细胞的成熟。来自美国Baylor医学院(BCM)的研究人员在最新《自然》上发表的新文章指出,没有一种叫做Nix的蛋白质,则细胞无法有效地在线粒体中“自我消化”,进而变得短命并导致贫血的发生。... ...全文

  • 汤汤 (浙江) 基因组大规模筛选新技术助力癌症研究

    发表于 2008-02-17

    多年来生物学家一直在搜寻癌细胞的弱点,以期找到对付癌症的线索。美国科学家近日研究出了一种基因组大规模筛选技术,有望提供一种强大的经济有效的方法以挑选出对付癌症的新药靶。相关论文发表在2月1日的《科学》(Science)上。   2005年,美国国立卫生研究院斥资15亿美元发起“癌症基因组地图”(TCGA)项目,目的是搜寻在很多癌症... ...全文

  • 汤汤 (浙江) 皮层放射状迁移的导向分子的发现

    发表于 2008-02-17

    大脑皮层神经元迁移的调节机制是发育神经生物学中尚未解决的重大问题。通常认为,新生的锥体神经元从生发区向皮层上层迁移依赖于放射状胶质纤维的导引。而且皮层板层结构的形成受迁移神经元与胶质纤维的黏附及脱离机制所影响。长久以来,人们一直忽略了另一种潜在的调节机制:即分泌性分子的浓度梯度用于指导皮层神经元的放射状迁... ...全文

  • plant Structural and Functional Analysis of SGT1 Reveals That Its Interaction with HSP

    发表于 2007-12-06

    Related Articles Structural and Functional Analysis of SGT1 Reveals That Its Interaction with HSP90 Is Required for the Accumulation of Rx, an R Protein Involved in Plant Immunity. Plant Cell. 2007 Nov 21; Authors: Botër M, Amigues B, Peart J, Breuer C, Kadota Y, Casais... ...全文

  • plant Arabidopsis MALE STERILITY1 Encodes a PHD-Type Transcription Factor and Regulate

    发表于 2007-12-06

    Related Articles Arabidopsis MALE STERILITY1 Encodes a PHD-Type Transcription Factor and Regulates Pollen and Tapetum Development. Plant Cell. 2007 Nov 21; Authors: Ito T, Nagata N, Yoshiba Y, Ohme-Takagi M, Ma H, Shinozaki K The Arabidopsis thaliana MALE STERILITY1 ... ...全文

  • plant MALE STERILITY1 Is Required for Tapetal Development and Pollen Wall Biosynthesis

    发表于 2007-12-06

    Related Articles MALE STERILITY1 Is Required for Tapetal Development and Pollen Wall Biosynthesis. Plant Cell. 2007 Nov 21; Authors: Yang C, Vizcay-Barrena G, Conner K, Wilson ZA The Arabidopsis thaliana MALE STERILITY1 (MS1) gene is critical for viable pollen format... ...全文

  • neuroscience Long-term speeding in perceptual switches mediated by attention-dependent plasti

    发表于 2007-12-06

    Related Articles Long-term speeding in perceptual switches mediated by attention-dependent plasticity in cortical visual processing. Neuron. 2007 Nov 22;56(4):741-53 Authors: Suzuki S, Grabowecky M Binocular rivalry has been extensively studied to understand the mech... ...全文

  • neuroscience Selective Amplification of Stimulus Differences during Categorical Processing of

    发表于 2007-12-06

    Related Articles Selective Amplification of Stimulus Differences during Categorical Processing of Speech. Neuron. 2007 Nov 22;56(4):726-40 Authors: Raizada RD, Poldrack RA The brain's perceptual stimuli are constantly changing: some of these changes are treated as in... ...全文

  • neuroscience Motor cortex gates vibrissal responses in a thalamocortical projection pathway.

    发表于 2007-12-06

    Related Articles Motor cortex gates vibrissal responses in a thalamocortical projection pathway. Neuron. 2007 Nov 22;56(4):714-25 Authors: Urbain N, Deschênes M Higher-order thalamic nuclei receive input from both the cerebral cortex and prethalamic sensory path... ...全文

  • neuroscience Gain modulation by nicotine in macaque v1.

    发表于 2007-12-06

    Related Articles Gain modulation by nicotine in macaque v1. Neuron. 2007 Nov 22;56(4):701-13 Authors: Disney AA, Aoki C, Hawken MJ Acetylcholine is a ubiquitous cortical neuromodulator implicated in cognition. In order to understand the potential for acetylcholine to... ...全文

  • neuroscience Retinal adaptation to object motion.

    发表于 2007-12-06

    Related Articles Retinal adaptation to object motion. Neuron. 2007 Nov 22;56(4):689-700 Authors: Olveczky BP, Baccus SA, Meister M Due to fixational eye movements, the image on the retina is always in motion, even when one views a stationary scene. When an object mov... ...全文

  • neuroscience A GluR1-cGKII Interaction Regulates AMPA Receptor Trafficking.

    发表于 2007-12-06

    Related Articles A GluR1-cGKII Interaction Regulates AMPA Receptor Trafficking. Neuron. 2007 Nov 22;56(4):670-88 Authors: Serulle Y, Zhang S, Ninan I, Puzzo D, McCarthy M, Khatri L, Arancio O, Ziff EB Trafficking of AMPA receptors (AMPARs) is regulated by specific in... ...全文

  • neuroscience PKA Activation Bypasses the Requirement for UNC-31 in the Docking of Dense Core

    发表于 2007-12-06

    Related Articles PKA Activation Bypasses the Requirement for UNC-31 in the Docking of Dense Core Vesicles from C. elegans Neurons. Neuron. 2007 Nov 22;56(4):657-69 Authors: Zhou KM, Dong YM, Ge Q, Zhu D, Zhou W, Lin XG, Liang T, Wu ZX, Xu T The nematode C. elegans pr... ...全文

  • neuroscience Kalirin-7 controls activity-dependent structural and functional plasticity of de

    发表于 2007-12-06

    Related Articles Kalirin-7 controls activity-dependent structural and functional plasticity of dendritic spines. Neuron. 2007 Nov 22;56(4):640-56 Authors: Xie Z, Srivastava DP, Photowala H, Kai L, Cahill ME, Woolfrey KM, Shum CY, Surmeier DJ, Penzes P Activity-depend... ...全文

  • neuroscience Sez-6 proteins affect dendritic arborization patterns and excitability of cortic

    发表于 2007-12-06

    Related Articles Sez-6 proteins affect dendritic arborization patterns and excitability of cortical pyramidal neurons. Neuron. 2007 Nov 22;56(4):621-39 Authors: Gunnersen JM, Kim MH, Fuller SJ, De Silva M, Britto JM, Hammond VE, Davies PJ, Petrou S, Faber ES, Sah P, Tan SS ... ...全文

  • neuroscience The Ubiquitin Ligase Phr1 Regulates Axon Outgrowth through Modulation of Microtu

    发表于 2007-12-06

    Related Articles The Ubiquitin Ligase Phr1 Regulates Axon Outgrowth through Modulation of Microtubule Dynamics. Neuron. 2007 Nov 22;56(4):604-20 Authors: Lewcock JW, Genoud N, Lettieri K, Pfaff SL To discover new genes involved in axon navigation, we conducted a forw... ...全文

  • neuroscience Nonapical symmetric divisions underlie horizontal cell layer formation in the de

    发表于 2007-12-06

    Related Articles Nonapical symmetric divisions underlie horizontal cell layer formation in the developing retina in vivo. Neuron. 2007 Nov 22;56(4):597-603 Authors: Godinho L, Williams PR, Claassen Y, Provost E, Leach SD, Kamermans M, Wong RO Symmetric cell divisions... ...全文

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